The SLC11A1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SLC11A1. This antibody recognizes Human, and Rat antigen. The SLC11A1 Antibody has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes